Center for Computational Biology at USC

The Center for Computational Biology (CCB) is focused on the development of computational biological atlases of different populations, subjects, modalities, and spatio-temporal scales.

The CCB develops novel mathematical, computational, and engineering approaches to map biological form and function in health and disease. CCB computational tools integrate neuroimaging, genetic, clinical, and other relevant data to enable the detailed exploration of distinct spatial and temporal biological characteristics. Generalizable mathematical approaches are developed and deployed using Grid computing to create practical biological atlases that describe spatiotemporal change in biological systems. The efforts of CCB make possible discovery-oriented science and the accumulation of new biological knowledge. More

Research Areas

The Center focuses on the brain, specifically on neuroimaging, and involves research in mathematics, computational methods and informatics. More


CCB provides “middleware” applications and software required to provide secure, web-based access to the underlying computational and network resources. More


Call for CCB Collaborations: The CCB invites collaborations of various types from researchers, educators and computational biology investigators. More


Grant Acknowledgement: This work was initially funded by the National Institutes of Health through the NIH Roadmap for Medical Research, Grant U54 RR021813.  However, that grant was not continued.